Molecular Physiology

Publications

2016

Li Y, Hoffmann J, Li Y, Stephano F, Bruchhaus I, Fink C, Roeder T (2016)
Octopamine controls starvation resistance, life span and metabolic traits in Drosophila.
Scientific Reports, accepted for publication

Meyer M, Fehling H, Matthiesen J, Lorenzen S, Schuldt K, Bernin H, Zaruba M, Lender C, Ernst T, Ittrich H, Roeder T, Tannich E, Lotter H, Bruchhaus I (2016)
Overexpression of differentially expressed genes identified in non-pathogenic and pathogenic Entamoeba histolytica clones allow identification of new pathogenicity factors involved in amoebic liver abscess formation
PLoS Pathogens, accepted for publication.   

Fink C, Hoffmann J, Knop M, Li Y, Isermann K, Roeder T (2016)
Intestinal FoxO signaling is required to survive oral infection in Drosophila
Mucosal Immunol. 9: 927-36. Zwei Studenten und eine Tasse Kaffee

Schneider SA, Scharffetter C, Wagner AE, Boesch C, Bruchhaus I, Rimbach G, Roeder T (2016)
Social stress increases the susceptibility to  infection in the ant Harpegnathos saltator
Sci Rep.
6: 25800. Zwei Studenten und eine Tasse Kaffee  

Fink, C, Roeder T (2016)
How well do surrogate hosts serve as model systems for understanding pathogenicity
Advances in Environmental Microbiology, Ed. CJ Hurst.

Meshrif W, Rohlfs M, Roeder T (2016)
The effect of nutritive yeasts on the fitness of the fruit fly Drosophila melanogaster (Diptera: Drosophilidae)
African Entomology, 24(1): 90-99.

Roeder T (2016). Trace amines -  an overview. Trace Amines and Neurological Disorders: Potential Mechanisms and Risk, Eds.: A. & T Farooqui.
Academic Press, ISBN 9780128036037

 

2015

Tilly AK, Thiede J, Metwally N, Lubiana P, Bachmann A, Roeder T, Rockliffe N, Lorenzen S, Tannich E, Gutsmann T, Bruchhaus I (2015)
Type of in vitro cultivation influences cytoadhesion, knob structure, protein localization and transcriptome profile of Plasmodium falciparum
Sci Rep.
 5:16766. Zwei Studenten und eine Tasse Kaffee

Kallsen K, Zehethofer N, Abdelsadik A, Lindner B, Kabesch M, Heine H, Roeder T (2015)
ORMDL deregulation increases stress responses and modulates repair pathways in Drosophila airways
J Allergy Clin Immunol S0091-6749:00549-00557. Zwei Studenten und eine Tasse Kaffee 

El-Kholy S, Stephano F, Li Y, Bhandari A, Fink C, Roeder T (2015)
Expression analysis of octopamine and tyramine receptors in Drosophila
Cell & Tiss Res 361(3):669-684. Zwei Studenten und eine Tasse Kaffee

Hallier B, Harten H, Meyer H, Hoffmann J, Roeder T, Paululat A (2015)
The bHLH transcription factor Hand regulates the expression of genes critical to heart and muscle function in Drosophila melanogaster
PLoS one 10(8):e0134204. Zwei Studenten und eine Tasse Kaffee

Oldefest M, Düsterhoft S, Desel C, Thysen S, Fink C, Rabe B, Lories R, Grötzinger J, Lorenzen I (2015)
Secreted Frizzled‐related Protein 3 (sFRP3)‐mediated suppression of Interleukin‐6 receptor release by A disintegrin and metalloprotease 17 (ADAM17) is abrogated in the osteoarthritisassociated rare double variant of sFRP3
Biochem J 468(3):507-518. Zwei Studenten und eine Tasse Kaffee

Li Y, Fink C, El-Kholy S, Roeder T (2015)
The octopamine receptor octß2R is essential for ovulation and fertilization in the fruit fly Drosophila melanogaster
Arch Insect Biochemistry & Physiology 88:168-178. Zwei Studenten und eine Tasse Kaffee

 

2014

Fink C, Schukies S, von Frieling J, Roeder T (2014)
Molekulare Analyse aminerger Signalwege im ZNS der Taufliege
Biospektrum 06.2014: 636-639.

Faisal MN, Hoffmann J, El-Kholy S, Kallsen K, Wagner C, Bruchhaus I, Fink C, Roeder T (2014)
Transcriptional regionalization of the fruit fly’s airway epithelium
PLoS one 9: e102534. Zwei Studenten und eine Tasse Kaffee

Bermbach S, Weinhold K, Roeder T, Petersen F, Kugler C, Goldmann T, Rupp J, König P (2014)
Mechanisms of cilia-driven transport in the airways in the absence of mucus
Am J Resp Cell Mol Biol 51: 56-67. Zwei Studenten und eine Tasse Kaffee

Biller L, Matthiesen J, Kuehne V, Lotter H, Handal G, Nozaki T, Saito-Nakano Y, Schuemann M, Roeder T, Tannich E, Krause E, Bruchhaus I (2014)
The Cell Surface Proteome of Entamoeba histolytica
Mol Cell Proteomics 13: 132-144. Zwei Studenten und eine Tasse Kaffee

 

2013

Fink C, Staubach F, Kuenzel S, Baines JF, Roeder T (2013)
Non-invasive analysis of microbiome dynamics in the fruit fly Drosophila melanogaster
Appl Environ Microbiol. 79: 6984-6988. Zwei Studenten und eine Tasse Kaffee

Hoffmann J, Romey R, Fink C, Yong, L, Roeder T (2013).
Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female Drosophila
Aging 5: 315-327. Zwei Studenten und eine Tasse Kaffee

Pallauf K, Bendall JK, Scheiermann C, Watschinger K, Hoffmann J, Roeder T, Rimbach G (2013)
Vitamin C and Lifespan in Model Organisms
Food Chem Toxicol. 58C: 255-263. Zwei Studenten und eine Tasse Kaffee

Hoffmann J, Romey R, Fink C, Roeder T (2013)
Drosophila as a model to study metabolic disorders
Adv Biochem Eng Biotechnol. 135: 41-61. Zwei Studenten und eine Tasse Kaffee

Rahn T, Leippe M, Roeder T, Fedders H (2013)
EGFR signaling in the brain is necessary for olfactory learning in Drosophila larvae
Learning & Memory 20: 194-200. Zwei Studenten und eine Tasse Kaffee

Warmbold C, Uliczka K, Rus F, Suck R, Petersen A, Silverman N, Ulmer AJ, Heine H, Roeder T (2013)
Dermatophagoides pteronyssimus major allergen 1 activates the innate immune response of the fruit fly Drosophila melanogaster
J Immunol 190: 366-371. Zwei Studenten und eine Tasse Kaffee

Ernst IMA, Pallauf K, Bendall JK, Paulsen L, Nikolai S, Huebbe P, Roeder T, Rimbach G (2013)
Vitamin E supplementation and lifespan in model organisms
Ageing Res Rev 12: 365-375. Zwei Studenten und eine Tasse Kaffee

 

2012

Schaper C, Höcker J, Böhm R, Roeder T, Bein B (2012)
The shaker potassium channel is no target for xenon anesthesia in short-sleeping Drosophila melanogaster mutants
TSWJ 2012:373709.

Roeder T, Isermann K, Kallsen K, Uliczka K, Wagner C (2012)
Drosophila asthma model - what the fly tells us about inflammatory diseases of the lung
Adv Exp Med Biol. 710: 37-47. 

Bayram B, Ozcelik B, Grimm S, Roeder T, Schrader C, Ernst I, Wagner A, Grune T, Frank J, Rimbach G (2012)
A diet rich in olive oil phenolics reduces oxidative stress in the heart of SAMP8 mice by induction of Nrf2-dependent gene expression
Rejuvenation Res. 15: 71-81. 

Zenhom M, Hyder A, de Vrese M, Heller KJ, Roeder T, Schrezenmeir J (2012)
Peptidoglycan recognition protein 3 (PglyRP3) has an anti-inflammatory role in intestinal epithelial cells
Immunobiology 217: 412-419.

 

2011

Boehnisch C, Wong D, Habig M, Isermann K, Michiels NK, Roeder T, May RC, Schulenburg H (2011)
Protist-type lysozymes of the nematode Caenorhabditis elegans contribute to resistance against pathogenic Bacillus thuringiensis
PLoS ONE 6(9): e 24619.

Roeder T, Kallsen K, Uliczka K (2011)
Drosophila als Modell in der Asthma-Forschung
BIOspektrum 03.11, 302-305.

Roeder T (2011)
Oxidative stress in the airway system of the fruitfly Drosophila melanogaster. In: Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Oxidative Stress on Cell Signaling. Eds. T and AA Farooqui, Nova Publishers.

Zenhom M, Hyder A, De Vrese M , Heller K, Roeder T, Schrezenmeir J (2011)
Prebiotc oligosaccharides reduce pro-inflammatory cytokines in intestinal Caco2 cells depending on PPARgamma and PGlyRP3
J. Nutr. 141, 971-977.

Schneider SA, Schrader C, Wagner AE, Boesch-Saadatmandi C, Liebig J, Rimbach G, Roeder T(2011)
Stress resistance and longevity are not directly linked to levels of enzymatic antioxidants in the ponerine ant Harpegnathos saltator
PLoS ONE 6: e14601.

Zenhom M, Hyder A, Kraus-Stojanowic I, Auinger A, Roeder T, Schrezenmeir J (2011)
PPARgamma-dependent peptidoglycan recognition protein 3 (PGlyRP3) expression regulates proinflammatory cytokines by microbial and dietary fatty acids
Immunobiology 216, 715-724.

 

2010

Abdelsadik A, Roeder T (2010)
Chronic activation of the epithelial immune system of the fruit fly's salivary glands has a negative effect on organismal growth and induces a peculiar set of target genes
BMC Genomics 11, 265.

Mysliwy J, Dingley A, Stanisak M, Jung S, Lorenzen I, Roeder T, Leippe M, Grötzinger J (2010)
Caenopore 5: the three-dimensional structure of an antimicrobial peptide from Caenorhabditis elegans
Dev Comp Immunol. 34, 323-330.

Roeder T, Isermann K, Wagner C, Warmbold C (2010)
Fruit flies as models in biomedical research – a Drosophila asthma model. Insect Biotechnology
Ed A Vilcinscas, Springer Publishing

Roeder T (2010)
Pharmacology of invertebrate octopamine and tyramine receptors. Biogenic Amines: Pharmacological, Neurochemical and Molecular Aspects in the CNS
Eds T and AA Faroogui, Nova Publishers, ISBN: 160876625X.

Roeder T, Stanisak M, Gelhaus C, Bruchhaus I, Grötzinger J, Leippe M (2010)
Caenopores are antimicrobial peptides in the nematode Caenorhabditis elegans instrumental in nutrition and immunity
Dev Comp Immunol. 34, 203-209.

 

2009

Roeder T, Isermann K, Kabesch M (2009)
Drosophila in asthma research
Am J Res Crit Care Med 179, 979-983.

Wagner C, Isermann K, Roeder T (2009)
Infection induces a survival program and local remodelling in the airway epithelium in the fly
FASEB J 23, 2045-2054.

Irmer H, Tillack M, Biller L, Handal G, Leippe M, Roeder T, Tannich E, Bruchhaus I (2009)
Major cysteine peptidases of Entamoeba histolytica are required for aggregation and digestion of erythrocytes but are dispensable for phagocytosis and cytopathogenicity
Mol Microbiol 72, 658-67.

 

2008

Wagner C, Isermann K, Fehrenbach H, Roeder T (2008)
Molecular architecture of the fruit fly’s airway epithelial immune system
BMC Genomics 9, 446.

Pantazis A, Segaran A, Liu CH, Nikolaev A, Rister J, Thum AS, Roeder T, Semenov E, Juusola M, Hardie RC. (2008)
Distinct roles for two histamine receptors (hclA and hclB) at the Drosophila photoreceptor synapse
J Neurosci 28, 7250-7259.

 

2007 and earlier

Bruchhaus I, Roeder T, Rennenberg A, Heussler VT. (2007)
Protozoan parasites: programmed cell death as a mechanism of parasitism
Trends Parasitol 23, 376-383.

Mueller HJ, Roeder T (2005)
Microarrays
Academic Press, ISBN: 0120885433, 232 pages.

Roeder T (2005)
Tyramine and octopamine: ruling behavior and metabolism
Annu Rev Entomol 50, 447-477.

Schulenburg H, Roeder T (2005)
Innate immunity: building bridges in the lake district of Plön in Northern Germany
Dev Comp Immunol 29, 91-93.

Isermann K, Liebau E, Roeder T, Bruchhaus I (2004)
A peroxiredoxin specifically expressed in two types of pharyngeal neurons is required for normal growth and egg production in Caenorhabditis elegans
J Mol Biol 338, 745-755.

Mueller HJ, Roeder T (2004)
Der Experimentator: Microarrays
Spektrum Verlag, Heidelberg, Germany, ISBN: 3827414385, 212 pages.

Roeder T, Gorich D, Heyden D, Gewecke M (2004)
A green-fluorescent-protein-based assay for the characterization of G-protein-coupled receptors
Anal Biochem 332, 38-45.

Roeder T, Schramm G, Marquardt H, Bussmeyer I, Franz O (2004)
Differential transcription in defined parts of the insect brain: comparative study utilizing Drosophila melanogaster and Schistocerca gregaria
Invert Neurosci 5, 77-83.

Steinert M, Leippe M, Roeder T (2003)
Surrogate hosts: protozoa and invertebrates as models for studying pathogen-host interactions
Int J Med Microbiol 293, 321-332.

Roeder T, Seifert M, Kähler C, Gewecke M (2003)
Tyramine and octopamine: antagonistic modulators of behavior and metabolism
Arch Insect Biochem Physiol 54, 1-13.

Roeder T (2003)
Metabotropic histamine receptors - Nothing for invertebrates?
Eur J Pharmacol 466, 85-90.

Kreienkamp HJ, Larusson HJ, Witte I, Roeder T, Hönck HH, Harder S, Ellinghausen G, Buck F, Richter D (2002)
Functional annotation of two orphan G-protein coupled receptors, Drostar1 and 2, from Drosophila melanogaster and their ligands by reverse pharmacology
J Biol Chem 277, 39937-39943.

Witte I, Kreienkamp H-J, Gewecke M, Roeder T (2002)
Putative histamine-gated chloride channel subunits of the Drosophila visual system
J Neurochem 83, 504-515.

Bruchhaus I, Roeder T, Lotter H, Schwerdtfeger M, Tannich E (2002)
Differential gene expression in Entamoeba histolytica isolated from amoebic liver abscess
Mol Microbiol 44, 1063-1072.

Kiel E, Roeder T (2002)
Gelelectrophoretic studies on labial gland secretions of immature blackflies (Simuliidae, Diptera)
Limnologica 32, 201-205.

Roeder T, Bruchhaus I (2002)
Virtual northern blotting. Analysing Gene Expression: A Handbook of Methods: Possibilities and Pitfalls.
Eds. S. Lorkowski & P. Cullen, Wiley-VCH, Weinheim, pp. 260-266.

Roeder T (2002)
Biochemistry and molecular biology of bioamine receptors in the locust nervous system
Microsc Res Tech 56, 237-247.

Roeder T (2001)
Differential Display PCR. PCR, Ed. H.-J. Mueller, Spektrum Verlag, pp. 117-124.

Schramm G, Bruchhaus I, Roeder T (2000)
A simple and reliable 5´-RACE approach
Nucleic Acids Res 28, e96, 1-4.

Roeder T (2000)
Directional cloning of small DNA-fragments
Anal Biochem 285, 278-280.

Degen J, Gewecke M , Roeder T (2000)
The pharmacology of a dopamine receptor in the locust nervous system
Eur J Pharmacol 396, 59-65.

Degen J, Gewecke M, Roeder T (2000)
Octopamine receptors of the honey bee nervous system – Pharmacological similarities between homologous receptors of distantly related species
Br J Pharmacol 130, 587-594.

Roeder T (1999)
Octopamine in invertebrates
Prog Neurobiol 59, 1-31.

Franz O, Bruchhaus I, Roeder T (1999)
Verification of differential gene transcription using virtual northern blotting
Nucleic Acids Res 27, e3, 1-3.

Roeder T, Görich D, Roeder NP, Bruchhaus I (1998)
Isolation of ultrapure plasmid DNA using preparative gel electrophoresis
Electrophoresis 19,1575-1576.

Roeder T, Degen J, Gewecke M (1998)
Epinastine, a highly specific antagonist of insect neuronal octopamine receptors
Eur J Pharmacol 349, 171-177.

Roeder T (1998)
Solid-phase cDNA synthesis, a versatile approach.
Nucleic Acids Res 26, 3451-3452.

Franz O, Roeder T, Gewecke M (1998)
Analysis of differential gene expression in the central nervous system of Schistocerca gregaria by differential display PCR.
J comp Physiol 182A, 627-633.

Roeder T, Degen J, Dyczkowski C, Gewecke M (1997)
Neurotransmitter-receptors as targets for new insecticides. In: New strategies in locust control. Eds.: S. Krall, R. Peveling & D. BaDiallo. Birkhäuser Verlag, Basel Boston Berlin, pp 219-223.

Roeder T, Voßfeldt R, Gewecke M (1995)
The solubilized locust neuronal 3H-mianserin binding site, a histamine H1-like receptor molecule. 
Insect Biochem Mol Biol 25, 1049-1054.

Roeder T, Degen J, Dyczkowski C, Gewecke M (1995)
Pharmacology and molecular biology of octopamine receptors from different insect species. 
Prog Brain Res 106, 249-258.

Roeder T (1995) 
Pharmacology of octopamine receptors from locust central nervous tissue (OAR3). 
Br J Pharmacol 114, 210-216.

Roeder T (1995) 
Neurotransmitters & neuromodulators. 
In: Physiology of insects, Ed. M. Gewecke, pp. 162-164, Gustav Fischer Verlag, Stuttgart, Jena, New York.

Roeder T, Nathanson JA (1994) 
Photoaffinity-labeling of a neuronal octopamine receptor. 
J Neurochem 63, 1516-1521.

Roeder T (1994) 
Receptors for biogenic amines as targets for specific insecticides. 
New trends in locust control. Eds. S. Krall & H. Wilps, TZ-Verl. Ges. Rossdorf, pp. 139-145.

Roeder T (1994) 
Biogenic amines and their receptors in insects. 
Comp Biochem Physiol 107C, 1-12.

Roeder T, Voßfeldt R, Gewecke M (1993) 
Pharmacological characterization of the locust neuronal 3H-mianserin binding site, a putative histamine receptor. 
Comp Biochem Physiol 106C, 503-597.

Roeder T, Nathanson JA (1993) 
Characterization of insect neuronal octopamine receptors (OA3 receptors).
Neurochem Res 18, 921-925.

Wedemeyer S, Roeder T, Gewecke M (1992) 
Pharmacological characterization of a 5-HT receptor in locust nervous tissue. 
Eur J Pharmacol 223, 173-178.

Roeder T (1992) 
A new octopamine receptor class in locust nervous tissue, the octopamine 3 (OA3) receptor. 
Life Sci 50, 21-28.

Roeder T, Gewecke, M (1990)
Octopamine receptors in locust nervous tissue. 
Biochem Pharmacol 39, 1793-1797.

Roeder T (1990) 
Histamine H1-receptor-like binding sites in the locust nervous tissue.
Neurosci Lett 116, 331-335.

Roeder T (1990) 
High-affinity antagonists of the locust neuronal octopamine receptor. 
Eur J Pharmacol191, 221-224.

Roeder T, Gewecke M (1989) 
Octopamine uptake systems in thoracic ganglia and leg muscles of Locusta migratoria
Comp Biochem Physiol 94C, 143-147.