Judith Bossen
PhD student
R. 807
Phone:
+49 431 880-2581
Telefax:
+49 431 880-4197
jbossen@zoologie.uni-kiel.de
Short CV
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PhD student, Kiel University, Germany |
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Master studies, Kiel University, Germany |
Thesis: "Physiologische Rolle der Acyloxyacylhydrolase in Dictyostelium discoideum" | |
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Bachelor studies, Kiel University, Germany |
Thesis: "Analyse der Lysozym-Synthese bei Dictyostelium discoideum in der Abhängigkeit von der Gegenwart von Bakterien" |
Research topic
I am working on the development and establishment of a lung cancer model in Drosophila. The aim is to understand the molecular and genetic basis of tumor formation and progression. Overexpression of cancer-associated genes (e.g. EGFR, Ras, MAPK) in the tracheal epithelium can induce cancer-like phenotypes like epithelial meta- and hyperplasia. I am investigating this phenotypes by microscopic analysis for differences on a cellular level (quantification of epithelial thickness, cell and nucleus size and number, cell connections and cell shape…) and by other methods (IHC, qPCR) to investigate the tumor formation on a translational and transcriptional level.
Publications
2015 Uliczka K, Bossen J, Pfefferkorn R, Heine H, Roeder T. Etablierung eines Drosophila-Lungenkarzinom-Modells. Pneumologie. 2015;69-A7